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A Closer Look At An Emerging Psoriasis Therapy

Impoyz™ Cream (Encore Dermatology). A brand new concentration of a proven steroid may help treat patients with lower extremity psoriasis.

Tracey Vlahovic, DPM, notes Impoyz™ Cream consists of clobetasol propionate at a concentration of 0.025%, different from the 0.05% concentration that clinicians usually use. She says patients would use the high potency class 2 topical steroid for 14 days consecutively for psoriasis.

The manufacturer Encore Dermatology notes Impoyz Cream, which became available in May, is indicated for moderate to severe plaque psoriasis. The company notes that application site discoloration occurred in 1 percent of patients using Impoyz.

One advantage of Impoyz Cream is that it is propylene glycol-free, according to Dr. Vlahovic, a Clinical Professor in the Department of Podiatric Medicine at the Temple University School of Podiatric Medicine. As she notes, the American Contact Dermatitis Society named propylene glycol, found in many topical substances, the 2018 Allergen of the Year. Dr. Vlahovic adds the Impoyz Cream’s vehicle contains a stabilizer that keeps the active ingredient in and around the epidermis.

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